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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2wvj TTP Thymidine kinase, cytosolic 2.7.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2wvj TTPThymidine kinase, cytosolic 2.7.1.21 1.215
1xbt TTPThymidine kinase, cytosolic 2.7.1.21 0.977
2uz3 TTPThymidine kinase / 0.894
2b8t THMThymidine kinase / 0.855
5fuv THMThymidine kinase, putative / 0.839
5fuw THMThymidine kinase, putative / 0.796
1jtk THUCytidine deaminase 3.5.4.5 0.692
1ijj ATPActin, alpha skeletal muscle / 0.678
1ux0 THUCytidine deaminase 3.5.4.5 0.670
4o4e ATPKinase / 0.667
4o4f ATPKinase / 0.667
1kws UGAGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 / 0.666
2fav APRNonstructural polyprotein pp1a / 0.665
2fsn ADPArchaeal actin homolog / 0.664
4xcz T3QQdtf / 0.659
1p72 THMThymidine kinase / 0.654
2rcy NAPPyrroline-5-carboxylate reductase / 0.651