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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2wkm PFY Hepatocyte growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
2wkm PFYHepatocyte growth factor receptor 2.7.10.1 1.138
3g0e B49Mast/stem cell growth factor receptor Kit 2.7.10.1 0.691
2c3k ABOSerine/threonine-protein kinase Chk1 2.7.11.1 0.663
2jam J60Calcium/calmodulin-dependent protein kinase type 1G 2.7.11.17 0.657
2pe0 39Z3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.653