Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2wed PP6 Penicillopepsin-1 3.4.23.20

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2wed PP6Penicillopepsin-1 3.4.23.20 1.062
2web PP4Penicillopepsin-1 3.4.23.20 0.815
1ppl 1Z7Penicillopepsin-1 3.4.23.20 0.795
2wea PP6Penicillopepsin-1 3.4.23.20 0.779
1ppk IVVPenicillopepsin-1 3.4.23.20 0.771
1ppm 0P1Penicillopepsin-1 3.4.23.20 0.759
1bxq PP8Penicillopepsin-1 3.4.23.20 0.743
1gvw 0EMEndothiapepsin 3.4.23.22 0.736
3prs RITEndothiapepsin 3.4.23.22 0.668
2qzl IXSBeta-secretase 1 3.4.23.46 0.659
1od1 0QSEndothiapepsin 3.4.23.22 0.651