Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vo7 M05 cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2vo7 M05cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 1.006
3mvj XFEcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.787
3x2v ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2vo0 M03cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.741
3mv5 XFERAC-alpha serine/threonine-protein kinase 2.7.11.1 0.739
4xw4 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.730
3idc ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.726
4dg3 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.726
3idb ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.723
3zo1 SIJcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.719
1phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.714
2phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.714
4iak ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.713
4ib3 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.712
4iac ACPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.711
3x2w ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.710
3zo4 QWIcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.705
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.703
2vo3 M04cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.702
3mvh WFERAC-alpha serine/threonine-protein kinase 2.7.11.1 0.699
4iai ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.697
4xw5 ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.691
4dh5 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.690
4iaz ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.690
3gu5 ANPDeath-associated protein kinase 1 2.7.11.1 0.687
4oti MI1Serine/threonine-protein kinase N1 / 0.687
4h3q ANPMitogen-activated protein kinase 1 2.7.11.24 0.684
1ig1 ANPDeath-associated protein kinase 1 2.7.11.1 0.683
2qcs ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.679
4qny ANPMitogen activated protein kinase, putative / 0.678
4wbb ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.677
2b9j ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.676
1cdk ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.675
1o6k ANPRAC-beta serine/threonine-protein kinase 2.7.11.1 0.675
4gvj ADPNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.675
1j1b ANPGlycogen synthase kinase-3 beta 2.7.11.26 0.674
1jbp ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.673
2a19 ANPInterferon-induced, double-stranded RNA-activated protein kinase 2.7.11.1 0.673
4uak ADPSerine/threonine-protein kinase MRCK beta 2.7.11.1 0.672
1jkk ANPDeath-associated protein kinase 1 2.7.11.1 0.670
4hpt ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.669
1nvq UCNSerine/threonine-protein kinase Chk1 2.7.11.1 0.668
2w4k ADPDeath-associated protein kinase 1 2.7.11.1 0.667
2y9q ANPMitogen-activated protein kinase 1 2.7.11.24 0.667
1stc STUcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
1u5r ATPSerine/threonine-protein kinase TAO2 2.7.11.1 0.664
3x2u ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.663
5dt3 ATPAurora kinase A 2.7.11.1 0.661
2b9i ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.660
3q5i ANPProtein kinase, putative / 0.658
4gv1 0XZRAC-alpha serine/threonine-protein kinase 2.7.11.1 0.657
4krc AGSCyclin-dependent protein kinase PHO85 2.7.11.22 0.656
4oa9 ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.656
2ijm ATPFocal adhesion kinase 1 2.7.10.2 0.655
2uw0 GVKcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.655
2vuw 5IDSerine/threonine-protein kinase haspin 2.7.11.1 0.655
4crs AGSSerine/threonine-protein kinase N2 2.7.11.13 0.655
1ol5 ADPAurora kinase A 2.7.11.1 0.654
3mfs ANPPeripheral plasma membrane protein CASK 2.7.11.1 0.654
2acx ANPG protein-coupled receptor kinase 6 2.7.11.16 0.653
2uvz GVJcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.653
4cki ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.653
3a8w ATPProtein kinase C iota type 2.7.11.13 0.652
4iad ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.650
4u97 STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.650
5e92 ANPTGF-beta receptor type-2 2.7.11.30 0.650