Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2va7 C27 Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2va7 C27Beta-secretase 1 3.4.23.46 0.873
3wb4 0B3Beta-secretase 1 3.4.23.46 0.723
2ohq 7IPBeta-secretase 1 3.4.23.46 0.678
4o3m ADPBloom syndrome protein 3.6.4.12 0.664
3wb5 0B4Beta-secretase 1 3.4.23.46 0.663
4b70 WM9Beta-secretase 1 3.4.23.46 0.662
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.661
1nmd ATPMajor actin / 0.660
1wet GUNHTH-type transcriptional repressor PurR / 0.660
1xxj UNCUricase 1.7.3.3 0.660
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.660
2d09 FLVBiflaviolin synthase CYP158A2 / 0.660
2fzk CTPAspartate carbamoyltransferase regulatory chain / 0.660
2jey HLOAcetylcholinesterase 3.1.1.7 0.660
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.660
2zs9 ADPPantothenate kinase 2.7.1.33 0.660
3u9d ATPActin, alpha skeletal muscle / 0.660
3ypi PGHTriosephosphate isomerase 5.3.1.1 0.660
3zzn ADPL-lactate dehydrogenase / 0.660
5bnt NAPAspartate-semialdehyde dehydrogenase 1.2.1.11 0.660
4cdg ADPBloom syndrome protein 3.6.4.12 0.659
4acu QN7Beta-secretase 1 3.4.23.46 0.658
3kjg ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.655
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.654
4frs 0V6Beta-secretase 1 3.4.23.46 0.653