sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2rc5 | FAD | Ferredoxin--NADP reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2rc5 | FAD | Ferredoxin--NADP reductase | / | 1.489 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 1.214 | |
| 3zbt | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.214 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.195 | |
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.155 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 1.150 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.143 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.116 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.115 | |
| 1go2 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.109 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.108 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.099 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.097 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.096 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.095 | |
| 1qg0 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.095 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.088 | |
| 1gaw | FAD | Ferredoxin | / | 1.087 | |
| 1ogj | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.084 | |
| 1fnd | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.082 | |
| 1b2r | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.069 | |
| 1gaq | FAD | Ferredoxin | / | 1.069 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.067 | |
| 1gr1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.067 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.066 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.054 | |
| 3qfs | FAD | NADPH--cytochrome P450 reductase | / | 1.048 | |
| 4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.046 | |
| 3w5u | FAD | Ferredoxin | / | 1.042 | |
| 1bx0 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.038 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.035 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.025 | |
| 4y9u | FAD | NADPH--cytochrome P450 reductase | / | 1.021 | |
| 1qgz | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.016 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 1.012 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 1.011 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.009 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.007 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.005 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.992 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.991 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.985 | |
| 1ja1 | FAD | NADPH--cytochrome P450 reductase | / | 0.974 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.965 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.964 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.962 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.954 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.953 | |
| 4yaf | FAD | NADPH--cytochrome P450 reductase | / | 0.942 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.940 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.930 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.919 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.908 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.903 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.895 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.891 | |
| 1cqx | FAD | Flavohemoprotein | / | 0.883 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.872 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.871 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.870 | |
| 4y9r | FAD | NADPH--cytochrome P450 reductase | / | 0.870 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.869 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.867 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.857 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.852 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.846 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.833 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.831 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.831 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.827 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.825 | |
| 3w2f | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.811 | |
| 4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.807 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.802 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.788 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.779 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.777 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.761 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.758 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.754 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.749 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.746 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.745 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.726 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.725 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.720 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.715 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.713 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.710 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.706 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.702 | |
| 1eje | FMN | Protein MTH_152 | / | 0.698 | |
| 1rz1 | FAD | Phenol 2-hydroxylase component B | / | 0.695 | |
| 3a6q | FMN | FMN-binding protein | / | 0.692 | |
| 4ees | FMN | Phototropin-2 | 2.7.11.1 | 0.691 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.689 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.689 | |
| 3a6r | FMN | FMN-binding protein | / | 0.689 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.689 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.684 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.684 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.684 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.682 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.682 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.680 | |
| 1flm | FMN | FMN-binding protein | / | 0.679 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.679 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.676 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.675 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.675 | |
| 1wli | FMN | FMN-binding protein | / | 0.673 | |
| 2iml | FMN | Uncharacterized protein | / | 0.672 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.671 | |
| 1wlk | FMN | FMN-binding protein | / | 0.670 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.670 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.667 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.666 | |
| 2e83 | FMN | FMN-binding protein | / | 0.662 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.662 | |
| 3a20 | FMN | FMN-binding protein | / | 0.658 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.658 | |
| 3vy5 | FMN | FMN-binding protein | / | 0.656 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.656 | |
| 1gzf | NAD | Mono-ADP-ribosyltransferase C3 | 2.4.2 | 0.655 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.655 | |
| 2jkc | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.655 | |
| 3gfd | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.655 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.654 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.653 | |
| 3hjk | FAD | Vivid PAS protein VVD | / | 0.652 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.651 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.651 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.651 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.650 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.650 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.650 | |
| 5hy5 | FAD | Tryptophan 6-halogenase | / | 0.650 |