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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r3q 5SC Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
2r3q 5SCCyclin-dependent kinase 2 2.7.11.22 0.960
2r3i SCFCyclin-dependent kinase 2 2.7.11.22 0.780
2r3p 3SCCyclin-dependent kinase 2 2.7.11.22 0.752
2r3f SC8Cyclin-dependent kinase 2 2.7.11.22 0.736
2r3l SCWCyclin-dependent kinase 2 2.7.11.22 0.730
3pj8 404Cyclin-dependent kinase 2 2.7.11.22 0.717
2r3m SCXCyclin-dependent kinase 2 2.7.11.22 0.715
2b54 D05Cyclin-dependent kinase 2 2.7.11.22 0.709
2c68 CT6Cyclin-dependent kinase 2 2.7.11.22 0.708
2r3k SCQCyclin-dependent kinase 2 2.7.11.22 0.708
2c69 CT8Cyclin-dependent kinase 2 2.7.11.22 0.706
2r3r 6SCCyclin-dependent kinase 2 2.7.11.22 0.695
1w0x OLOCyclin-dependent kinase 2 2.7.11.22 0.692
2a0c CK9Cyclin-dependent kinase 2 2.7.11.22 0.688
4bgh 3I6Cyclin-dependent kinase 2 2.7.11.22 0.688
3le6 2BZCyclin-dependent kinase 2 2.7.11.22 0.683
1y8y CT7Cyclin-dependent kinase 2 2.7.11.22 0.680
2r3j SCJCyclin-dependent kinase 2 2.7.11.22 0.678
3dog NNNCyclin-dependent kinase 2 2.7.11.22 0.677
2btr U73Cyclin-dependent kinase 2 2.7.11.22 0.670
2vtj LZ4Cyclin-dependent kinase 2 2.7.11.22 0.665
4fkv 61KCyclin-dependent kinase 2 2.7.11.22 0.665
1ckp PVBCyclin-dependent kinase 2 2.7.11.22 0.660
2c6t DT5Cyclin-dependent kinase 2 2.7.11.22 0.660
3ezr EZRCyclin-dependent kinase 2 2.7.11.22 0.659
3r1s X73Cyclin-dependent kinase 2 2.7.11.22 0.659
1gii 1PUCyclin-dependent kinase 2 2.7.11.22 0.658
4fkt 48KCyclin-dependent kinase 2 2.7.11.22 0.654
2vts LZCCyclin-dependent kinase 2 2.7.11.22 0.650