Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r2m I50 Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2r2m I50Prothrombin 3.4.21.5 1.028
3c27 DKKProthrombin 3.4.21.5 0.868
1z71 L17Prothrombin 3.4.21.5 0.836
1mu6 CDAProthrombin 3.4.21.5 0.832
1mu8 CDBProthrombin 3.4.21.5 0.825
1sl3 170Prothrombin 3.4.21.5 0.800
1t4v 14AProthrombin 3.4.21.5 0.768
1mue CDDProthrombin 3.4.21.5 0.754
1nm6 L86Prothrombin 3.4.21.5 0.743
3c1k T15Prothrombin 3.4.21.5 0.731
1c4u IH1Prothrombin 3.4.21.5 0.688
4bao MVFProthrombin 3.4.21.5 0.686
4bah MELProthrombin 3.4.21.5 0.685
1k22 MELProthrombin 3.4.21.5 0.684
2bdy UNBProthrombin 3.4.21.5 0.680
1o0d 163Prothrombin 3.4.21.5 0.675
4bak M67Prothrombin 3.4.21.5 0.669
4ban M6SProthrombin 3.4.21.5 0.667
4ayv 9MQProthrombin 3.4.21.5 0.666
2bxt C2DProthrombin 3.4.21.5 0.664
4ax9 N5NProthrombin 3.4.21.5 0.663
2a2x NA9Prothrombin 3.4.21.5 0.662
3hat GLY_VAL_ARG_RNGProthrombin 3.4.21.5 0.662
1k21 IGNProthrombin 3.4.21.5 0.655