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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2qu5 276 Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2qu5 276Vascular endothelial growth factor receptor 2 2.7.10.1 1.236
2qu6 857Vascular endothelial growth factor receptor 2 2.7.10.1 0.904
4fny I3KALK tyrosine kinase receptor 2.7.10.1 0.673
1uwh BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.662
4tyj 0LIFibroblast growth factor receptor 4 2.7.10.1 0.656
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 0.655