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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2puj HPZ 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3.7.1.8

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2puj HPZ2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3.7.1.8 0.902
3v1m HPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3.7.1.8 0.855
2rht C1E2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3.7.1.8 0.780
2puh HPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase 3.7.1.8 0.729
4a9s RU9Serine/threonine-protein kinase Chk2 2.7.11.1 0.661