Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pir DHT Androgen receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2pir DHTAndrogen receptor / 1.219
2piv DHTAndrogen receptor / 1.093
2pix DHTAndrogen receptor / 1.078
2piu DHTAndrogen receptor / 1.069
1t7f DHTAndrogen receptor / 1.061
1t63 DHTAndrogen receptor / 1.059
2z4j DHTAndrogen receptor / 1.057
1t76 DHTAndrogen receptor / 1.053
4ofu DHTAndrogen receptor / 1.053
4oed DHTAndrogen receptor / 1.039
1t7t DHTAndrogen receptor / 1.034
1t7m DHTAndrogen receptor / 1.018
1t73 DHTAndrogen receptor / 0.999
2pkl DHTAndrogen receptor / 0.989
1t5z DHTAndrogen receptor / 0.979
2pio DHTAndrogen receptor / 0.832
2pit DHTAndrogen receptor / 0.832
4k7a DHTAndrogen receptor / 0.818
2pnu ENMAndrogen receptor / 0.815
4oey DHTAndrogen receptor / 0.813
4oea DHTAndrogen receptor / 0.810
1xow R18Androgen receptor / 0.806
2qpy DHTAndrogen receptor / 0.805
1xj7 DHTAndrogen receptor / 0.788
1t74 DHTAndrogen receptor / 0.783
1t65 DHTAndrogen receptor / 0.767
2ama DHTAndrogen receptor / 0.766
2piw DHTAndrogen receptor / 0.758
4ofr DHTAndrogen receptor / 0.755
2q7i TESAndrogen receptor / 0.734
1xq3 R18Androgen receptor / 0.733
4oez DHTAndrogen receptor / 0.731
2piq DHTAndrogen receptor / 0.730
1t79 DHTAndrogen receptor / 0.727
2ao6 R18Androgen receptor / 0.724
2pip DHTAndrogen receptor / 0.721
2aa6 STRMineralocorticoid receptor / 0.717
1t7r DHTAndrogen receptor / 0.715
2ylp TESAndrogen receptor / 0.715
4e5l DBHPolymerase acidic protein / 0.707
1i5r HYCEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.705
2q7k TESAndrogen receptor / 0.701
3vhu SNLMineralocorticoid receptor / 0.700
1lho AOMSex hormone-binding globulin / 0.691
3oll ESTEstrogen receptor beta / 0.691
2q7j TESAndrogen receptor / 0.687
1lri CLRBeta-elicitin cryptogein / 0.678
1lhn AONSex hormone-binding globulin / 0.677
3nhx ASDSteroid Delta-isomerase 5.3.3.1 0.677
4at2 ASDPossible succinate dehydrogenase / 0.668
4hlw TESAndrogen receptor / 0.667
2j7x ESTEstrogen receptor beta / 0.663
2ylo TESAndrogen receptor / 0.663
2am9 TESAndrogen receptor / 0.661
3nbr ASDSteroid Delta-isomerase 5.3.3.1 0.659
1xu7 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.652