Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pdq 47D Aldose reductase 1.1.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2pdq 47DAldose reductase 1.1.1.21 1.042
2fz8 ZSTAldose reductase 1.1.1.21 0.926
2pdi ZSTAldose reductase 1.1.1.21 0.920
2pdm ZSTAldose reductase 1.1.1.21 0.919
1z3n 3NAAldose reductase 1.1.1.21 0.918
2hv5 ZSTAldose reductase 1.1.1.21 0.917
3len ZSTAldose reductase 1.1.1.21 0.905
2fz9 ZSTAldose reductase 1.1.1.21 0.883
2hvo ZSTAldose reductase 1.1.1.21 0.882
2hvn ZSTAldose reductase 1.1.1.21 0.881
2pdb ZSTAldose reductase 1.1.1.21 0.873
2pdx ZSTAldose reductase 1.1.1.21 0.873
2duz ZSTAldose reductase 1.1.1.21 0.872
3m0i ZSTAldose reductase 1.1.1.21 0.857
2pdh 47DAldose reductase 1.1.1.21 0.856
2pd5 ZSTAldose reductase 1.1.1.21 0.832
2dv0 ZSTAldose reductase 1.1.1.21 0.827
1frb ZSTAldose reductase-related protein 2 / 0.818
3g5e Q74Aldose reductase 1.1.1.21 0.794
4gca 2X9Aldose reductase 1.1.1.21 0.760
2pdu 393Aldose reductase 1.1.1.21 0.747
2pdg 47DAldose reductase 1.1.1.21 0.740
3mb9 ZSTAldose reductase 1.1.1.21 0.733
2pdj 393Aldose reductase 1.1.1.21 0.729
2pdf ZSTAldose reductase 1.1.1.21 0.727
3ghu LDTAldose reductase 1.1.1.21 0.713
3ghs LDTAldose reductase 1.1.1.21 0.711
2pzn 393Aldose reductase 1.1.1.21 0.704
1t41 ID5Aldose reductase 1.1.1.21 0.701
1us0 LDTAldose reductase 1.1.1.21 0.700
2i16 LDTAldose reductase 1.1.1.21 0.700
2i17 LDTAldose reductase 1.1.1.21 0.700
2pdp 393Aldose reductase 1.1.1.21 0.700
1t40 ID5Aldose reductase 1.1.1.21 0.695
2is7 2CLAldose reductase 1.1.1.21 0.690
2pdc 393Aldose reductase 1.1.1.21 0.687
2ikj 393Aldose reductase 1.1.1.21 0.686
3ght LDTAldose reductase 1.1.1.21 0.677
3lbo LDTAldose reductase 1.1.1.21 0.673
3mc5 393Aldose reductase 1.1.1.21 0.671
2dux ZSTAldose reductase 1.1.1.21 0.666
3m4h 388Aldose reductase 1.1.1.21 0.666
3m64 393Aldose reductase 1.1.1.21 0.666
3lz5 LDTAldose reductase 1.1.1.21 0.663
3ld5 LDTAldose reductase 1.1.1.21 0.660
2inz OHPAldose reductase 1.1.1.21 0.657
2qxw LDTAldose reductase 1.1.1.21 0.657
3ghr LDTAldose reductase 1.1.1.21 0.657
3t42 3T4Aldose reductase 1.1.1.21 0.657
2iki 388Aldose reductase 1.1.1.21 0.656
3lql LDTAldose reductase 1.1.1.21 0.655
2iqd LPAAldose reductase 1.1.1.21 0.653
2pdn 47DAldose reductase 1.1.1.21 0.653