Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pa3 NAI D-3-phosphoglycerate dehydrogenase 1.1.1.95

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2pa3 NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 1.061
1yba NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.906
2p9c NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.861
2p9g NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.836
3oet NADErythronate-4-phosphate dehydrogenase / 0.830
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.783
2p9e NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.782
1dxy NADD-2-hydroxyisocaproate dehydrogenase 1.1.1 0.763
2o4c NADErythronate-4-phosphate dehydrogenase / 0.763
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.750
2vhw NAIAlanine dehydrogenase 1.4.1.1 0.739
2vhz NAIAlanine dehydrogenase 1.4.1.1 0.734
2ekl NADD-3-phosphoglycerate dehydrogenase / 0.733
3wsw NADL-lactate dehydrogenase / 0.730
1j49 NADD-lactate dehydrogenase 1.1.1.28 0.727
1t2d NADL-lactate dehydrogenase 1.1.1.27 0.725
1psd NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.723
2fn7 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.719
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.715
3kb6 NADD-lactate dehydrogenase / 0.714
4nd3 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.714
1hku NADC-terminal-binding protein 1 1.1.1 0.712
3qvw NADMyo-inositol-1-phosphate synthase (Ino1) / 0.712
4dl9 NADS-(hydroxymethyl)glutathione dehydrogenase / 0.710
3qvs NADMyo-inositol-1-phosphate synthase (Ino1) / 0.706
1pzh NADLactate dehydrogenase / 0.704
1x7d NADPutative ornithine cyclodeaminase / 0.702
2a92 NAIL-lactate dehydrogenase / 0.701
1t2c NAIL-lactate dehydrogenase 1.1.1.27 0.696
3cin NADMyo-inositol-1-phosphate synthase-related protein / 0.696
3n7u NADFormate dehydrogenase, chloroplastic/mitochondrial / 0.696
2vhx NADAlanine dehydrogenase 1.4.1.1 0.695
1u7h NADPutative ornithine cyclodeaminase / 0.693
4j49 NAIUncharacterized protein / 0.691
4nd2 A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.691
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.690
5dt9 NADErythronate-4-phosphate dehydrogenase / 0.690
1sow NADL-lactate dehydrogenase 1.1.1.27 0.689
4ros APRMalate dehydrogenase / 0.689
1j0x NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.688
2dph NADFormaldehyde dismutase / 0.688
2x0i NAIMalate dehydrogenase / 0.685
3qvt NAIMyo-inositol-1-phosphate synthase (Ino1) / 0.684
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.683
3qvx NADMyo-inositol-1-phosphate synthase (Ino1) / 0.682
1sc6 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.679
2hjr APRMalate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase / 0.679
2a94 AP0L-lactate dehydrogenase 1.1.1.27 0.678
1bdm NAXMalate dehydrogenase / 0.676
1pzg A3DLactate dehydrogenase / 0.676
4yag NAIC alpha-dehydrogenase / 0.676
1lsj NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.675
2aa3 AP0L-lactate dehydrogenase / 0.675
4j49 NADUncharacterized protein / 0.675
2nad NADFormate dehydrogenase / 0.673
2ome NADC-terminal-binding protein 2 / 0.673
4njo NADD-3-phosphoglycerate dehydrogenase, putative / 0.673
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.669
4xyb NDPFormate dehydrogenase / 0.669
1pzf A3DLactate dehydrogenase / 0.667
2y99 NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase 1.3.1.56 0.667
4xq9 NADHomospermidine synthase 2.5.1.44 0.667
1la2 NADInositol-3-phosphate synthase 5.5.1.4 0.666
4wlv NADMalate dehydrogenase, mitochondrial 1.1.1.37 0.666
1f17 NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.665
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.665
4o59 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.665
5c7o NADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific 1.2.1.12 0.665
4j4b NAIUncharacterized protein / 0.664
1e6w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.663
1o6z NADMalate dehydrogenase / 0.663
1vsv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.663
3jyq NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.663
4lcj NADC-terminal-binding protein 2 / 0.663
4k9d NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.662
2g5c NADPrephenate dehydrogenase / 0.661
4e5k NADPhosphonate dehydrogenase 1.20.1.1 0.661
1dss NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.660
1j5p NADL-aspartate dehydrogenase 1.4.1.21 0.660
4e5n NADPhosphonate dehydrogenase 1.20.1.1 0.660
2voj NADAlanine dehydrogenase 1.4.1.1 0.659
3jyp NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.659
4l4s NAIL-lactate dehydrogenase A chain 1.1.1.27 0.658
2hu2 NADC-terminal binding protein 1 / 0.657
2wsb NADGalactitol dehydrogenase / 0.657
4cpd NADAlcohol dehydrogenase / 0.657
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.657
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.657
1u1i NADMyo-inositol-1-phosphate synthase (Ino1) / 0.656
1h2h NADL-aspartate dehydrogenase 1.4.1.21 0.655
1xcb NADRedox-sensing transcriptional repressor Rex / 0.655
6adh NADAlcohol dehydrogenase E chain 1.1.1.1 0.655
1b8v NADMalate dehydrogenase / 0.654
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.653
1szj NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.653
3jyo NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.653
4e5p NADPhosphonate dehydrogenase 1.20.1.1 0.653
1ib6 NADMalate dehydrogenase / 0.652
1r37 NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.652
4rvu NDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) / 0.652
4jk3 NADUncharacterized protein / 0.651
4z0p NDPNAD-dependent dehydrogenase / 0.651