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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2p2i 608 Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2p2i 608Vascular endothelial growth factor receptor 2 2.7.10.1 1.205
3efl 706Vascular endothelial growth factor receptor 2 2.7.10.1 0.924
2hz0 GINTyrosine-protein kinase ABL1 2.7.10.2 0.742
3cp9 C19Vascular endothelial growth factor receptor 2 2.7.10.1 0.706
2qu6 857Vascular endothelial growth factor receptor 2 2.7.10.1 0.694
3hng 8STVascular endothelial growth factor receptor 1 2.7.10.1 0.674
4u0i 0LIMast/stem cell growth factor receptor Kit 2.7.10.1 0.652