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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ozo ANP Tyrosine-protein kinase ZAP-70 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2ozo ANPTyrosine-protein kinase ZAP-70 2.7.10.2 1.014
4k2r ANPTyrosine-protein kinase ZAP-70 2.7.10.2 0.781
4fl3 ANPTyrosine-protein kinase SYK 2.7.10.2 0.705
4fl2 ANPTyrosine-protein kinase SYK 2.7.10.2 0.697
3fzp AGSProtein-tyrosine kinase 2-beta 2.7.10.2 0.676
4zse ANPEpidermal growth factor receptor 2.7.10.1 0.669
2itx ANPEpidermal growth factor receptor 2.7.10.1 0.661
4fg8 ATPCalcium/calmodulin-dependent protein kinase type 1 2.7.11.17 0.660
2wqe ADPAurora kinase A 2.7.11.1 0.659
5d4g U5PPolymerase acidic protein / 0.654
4xlv ACPInsulin receptor 2.7.10.1 0.653