sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 1.343 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 1.085 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 1.007 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.939 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 0.938 | |
| 1gaw | FAD | Ferredoxin | / | 0.936 | |
| 2rc5 | FAD | Ferredoxin--NADP reductase | / | 0.919 | |
| 1gaq | FAD | Ferredoxin | / | 0.899 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.893 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.892 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.890 | |
| 3w5u | FAD | Ferredoxin | / | 0.886 | |
| 1cqx | FAD | Flavohemoprotein | / | 0.885 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.885 | |
| 1ogj | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.883 | |
| 1ja1 | FAD | NADPH--cytochrome P450 reductase | / | 0.881 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.869 | |
| 1qg0 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.868 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.862 | |
| 1fnd | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.861 | |
| 1gr1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.860 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.859 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.857 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.857 | |
| 1go2 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.856 | |
| 4yaf | FAD | NADPH--cytochrome P450 reductase | / | 0.850 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.849 | |
| 3zbt | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.849 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.848 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.848 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.843 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.836 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.835 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.833 | |
| 1bx0 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.832 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.832 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.832 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.824 | |
| 1b2r | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.823 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.811 | |
| 3w2f | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.811 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.807 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.807 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.805 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.800 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.794 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.791 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.791 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.791 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.789 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.785 | |
| 3qfs | FAD | NADPH--cytochrome P450 reductase | / | 0.784 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.780 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.780 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.778 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.778 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.775 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.774 | |
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.772 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.770 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.761 | |
| 4k1x | FAD | NADPH:ferredoxin reductase | / | 0.760 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.758 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.755 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.754 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.753 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.752 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.749 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.749 | |
| 4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.749 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.744 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.742 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.741 | |
| 1qgz | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.741 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.740 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.739 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.738 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.738 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.736 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.731 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.731 | |
| 5cho | FAD | Flavin reductase | / | 0.731 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.729 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.729 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.728 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.725 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 0.720 | |
| 3a3b | RBF | Lumazine protein | / | 0.719 | |
| 4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.719 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.715 | |
| 1pkv | RBF | Riboflavin synthase | 2.5.1.9 | 0.715 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.715 | |
| 3bnk | FMN | Flavoredoxin | / | 0.714 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.712 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.712 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.712 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.711 | |
| 2i02 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.711 | |
| 1rz1 | FAD | Phenol 2-hydroxylase component B | / | 0.709 | |
| 4f07 | FAD | Styrene monooxygenase component 2 | / | 0.706 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.703 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.701 | |
| 1usc | FMN | Monooxygenase | / | 0.694 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.694 | |
| 3rh7 | FMN | Uncharacterized protein | / | 0.694 | |
| 1eje | FMN | Protein MTH_152 | / | 0.693 | |
| 2iml | FMN | Uncharacterized protein | / | 0.691 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.690 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.688 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.686 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.686 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.684 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.681 | |
| 3gh8 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.679 | |
| 1wlk | FMN | FMN-binding protein | / | 0.678 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.677 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.675 | |
| 3is2 | FAD | Vivid PAS protein VVD | / | 0.674 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.672 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.672 | |
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.670 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.670 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.670 | |
| 3a3g | DLZ | Lumazine protein | / | 0.669 | |
| 3sfd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.669 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.668 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.668 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.668 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.666 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.666 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.665 | |
| 4l82 | FMN | Uncharacterized protein | / | 0.665 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.664 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.663 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.663 | |
| 4qvb | F42 | F420H(2)-dependent reductase Rv1155 | 1.4.3.5 | 0.663 | |
| 2bac | FAD | Putative aminooxidase | / | 0.662 | |
| 2nr4 | FMN | Conserved protein | / | 0.661 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.661 | |
| 2bab | FAD | Putative aminooxidase | / | 0.660 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.658 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.658 | |
| 3hjk | FAD | Vivid PAS protein VVD | / | 0.658 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.656 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.656 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.655 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.655 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.654 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.653 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.653 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.653 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.652 | |
| 4y9u | FAD | NADPH--cytochrome P450 reductase | / | 0.651 | |
| 5efw | FMN | NPH1-1 | / | 0.651 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.650 |