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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2oh0 2PY cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2oh0 2PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 1.034
2jds L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.890
3kkv B99cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.831
2f7e 2EAcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.821
2uzw SS4cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.792
2jdv L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.771
2uzt SS3cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.763
5dgz L20Serine/threonine-protein kinase pim-1 2.7.11.1 0.739
2ojf 4PYcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.734
2uzu L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.721
3l9m L9McAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.708
2uzv SS5cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.701
3l9n L9NcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.701
1ydr IQPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.655
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.653
1ke7 LS3Cyclin-dependent kinase 2 2.7.11.22 0.650