Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ocf EST Estrogen receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2ocf ESTEstrogen receptor / 1.123
4pxm ESTEstrogen receptor / 0.954
2yja ESTEstrogen receptor / 0.952
3uud ESTEstrogen receptor / 0.937
2qgt EEDEstrogen receptor / 0.927
5hyr ESTEstrogen receptor / 0.920
1gwr ESTEstrogen receptor / 0.899
3l03 4OHEstrogen receptor / 0.899
2yat EEUEstrogen receptor / 0.896
5dxg ESTEstrogen receptor / 0.896
2j7x ESTEstrogen receptor beta / 0.891
2g5o DRQEstrogen receptor / 0.874
3q95 ESLEstrogen receptor / 0.873
5dx3 ESTEstrogen receptor / 0.867
4j26 ESTEstrogen receptor beta / 0.858
3oll ESTEstrogen receptor beta / 0.857
4j24 ESTEstrogen receptor beta / 0.852
2b1z 17MEstrogen receptor / 0.825
1g50 ESTEstrogen receptor / 0.792
1n35 CH1RNA-directed RNA polymerase lambda-3 2.7.7.48 0.744
1n38 U3HRNA-directed RNA polymerase lambda-3 2.7.7.48 0.744
1nmd ATPMajor actin / 0.744
1wet GUNHTH-type transcriptional repressor PurR / 0.744
1xxj UNCUricase 1.7.3.3 0.744
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.744
2fzk CTPAspartate carbamoyltransferase regulatory chain / 0.744
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.744
3cwq ADPParA family chromosome partitioning protein / 0.744
3u9d ATPActin, alpha skeletal muscle / 0.744
3ypi PGHTriosephosphate isomerase 5.3.1.1 0.744
3zzn ADPL-lactate dehydrogenase / 0.744
4e5l DBHPolymerase acidic protein / 0.744
5bnt NAPAspartate-semialdehyde dehydrogenase 1.2.1.11 0.744
1i5r HYCEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.728
1lhw ESMSex hormone-binding globulin / 0.708
1lhu ESTSex hormone-binding globulin / 0.706
3uzx AOX3-oxo-5-beta-steroid 4-dehydrogenase / 0.695
1s0x C3SNuclear receptor ROR-alpha / 0.694
3iw1 ASDSteroid C26-monooxygenase 1.14.13.141 0.688
3uzx AOM3-oxo-5-beta-steroid 4-dehydrogenase / 0.682
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.674
1lho AOMSex hormone-binding globulin / 0.673
2j7y E3OEstrogen receptor beta / 0.673
3gki CLRNiemann-Pick C1 protein / 0.670
1lri CLRBeta-elicitin cryptogein / 0.667
3uzz ASD3-oxo-5-beta-steroid 4-dehydrogenase / 0.667
4hlw TESAndrogen receptor / 0.667
2piu DHTAndrogen receptor / 0.666
5l7d CLRSmoothened homolog / 0.666
1a27 ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.664
4y8w STRSteroid 21-hydroxylase / 0.664
4oea DHTAndrogen receptor / 0.663
4oed DHTAndrogen receptor / 0.663
1y9r 1CAMineralocorticoid receptor / 0.661
3ipt EQUSteroid Delta-isomerase 5.3.3.1 0.661
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.660
1h48 C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4.6.1.12 0.660
1yra GDPGPN-loop GTPase PAB0955 / 0.660
2hru ADPPhosphoribosylformylglycinamidine synthase subunit PurL / 0.660
2hs4 ACPPhosphoribosylformylglycinamidine synthase subunit PurL / 0.660
2puf GUNHTH-type transcriptional repressor PurR / 0.660
2xtn GTPGTPase IMAP family member 2 / 0.660
3kjg ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.660
4cdg ADPBloom syndrome protein 3.6.4.12 0.660
4nxv GDPMitochondrial dynamics protein MID51 / 0.660
4o3m ADPBloom syndrome protein 3.6.4.12 0.660
3w5q 3KLVitamin D3 receptor / 0.658
4or0 NPSSerum albumin / 0.658
3cot STR3-oxo-5-beta-steroid 4-dehydrogenase / 0.656
4a2j AS0Progesterone receptor / 0.656
4b10 NHWGlycylpeptide N-tetradecanoyltransferase / 0.656
1xu7 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.654
1ya3 STRMineralocorticoid receptor / 0.654
1xf0 ASDAldo-keto reductase family 1 member C3 / 0.652
1kdm DHTSex hormone-binding globulin / 0.651
3p5p A3CTaxadiene synthase 4.2.3.17 0.650
4q0a 4OAVitamin D3 receptor A / 0.650