Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2obj VRV Serine/threonine-protein kinase pim-1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2obj VRVSerine/threonine-protein kinase pim-1 2.7.11.1 0.916
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
4e5l DBHPolymerase acidic protein / 0.744
3dcv 55ESerine/threonine-protein kinase pim-1 2.7.11.1 0.741
3bgq VX2Serine/threonine-protein kinase pim-1 2.7.11.1 0.740
3jy0 LYGSerine/threonine-protein kinase pim-1 2.7.11.1 0.714
3ma3 01ISerine/threonine-protein kinase pim-1 2.7.11.1 0.698
3pxy JWSCyclin-dependent kinase 2 2.7.11.22 0.686
5dgz L20Serine/threonine-protein kinase pim-1 2.7.11.1 0.686
3q3b 55EGlycogen synthase kinase-3 beta 2.7.11.26 0.685
4a7c E46Serine/threonine-protein kinase pim-1 2.7.11.1 0.677
1pmv 537Mitogen-activated protein kinase 10 2.7.11.24 0.674
1sdt MK1Gag-Pol polyprotein 3.4.23.16 0.668
2zdt 46CMitogen-activated protein kinase 10 2.7.11.24 0.668
1rek B8LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.666
1q8u H52cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.661
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2hzi JINTyrosine-protein kinase ABL1 2.7.10.2 0.653
2gdo 12CSerine/threonine-protein kinase Chk1 2.7.11.1 0.651
2xj1 XJ1Serine/threonine-protein kinase pim-1 2.7.11.1 0.651
4anm WULCasein kinase II subunit alpha 2.7.11.1 0.651
2c3i IYZSerine/threonine-protein kinase pim-1 2.7.11.1 0.650