Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2o1o RIS Putative farnesyl pyrophosphate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2o1o RISPutative farnesyl pyrophosphate synthase / 1.062
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.843
1rqj RISFarnesyl diphosphate synthase 2.5.1.10 0.838
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.814
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.814
4dem YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.812
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.806
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.805
4dxj 0M9Farnesyl pyrophosphate synthase / 0.800
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.798
4h5e YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.782
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.780
4h5c YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.780
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.772
3dyh 721Farnesyl pyrophosphate synthase / 0.768
3icz PB6Farnesyl pyrophosphate synthase / 0.748
2zev B71Geranylgeranyl pyrophosphate synthase / 0.747
3krf DSTGeranyl diphosphate synthase large subunit / 0.744
4l2x YL2Farnesyl pyrophosphate synthase 2.5.1.10 0.744
4q23 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.731
4dwb 0M7Farnesyl pyrophosphate synthase / 0.725
3ryw K9HFarnesyl pyrophosphate synthase, putative / 0.724
2e91 ZOLGeranylgeranyl pyrophosphate synthase / 0.716
1zw5 ZOLFarnesyl pyrophosphate synthase 2.5.1.10 0.706
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.702
3egt 722Farnesyl pyrophosphate synthase / 0.702
3rbm B73Farnesyl pyrophosphate synthase, putative / 0.692
1id0 ANPSensor protein PhoQ 2.7.13.3 0.691
2e95 B75Geranylgeranyl pyrophosphate synthase / 0.686
2olq ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.686
2z52 H23Geranylgeranyl pyrophosphate synthase / 0.684
1xjk DGTVitamin B12-dependent ribonucleotide reductase / 0.683
4qm6 GTPMetallophosphoesterase / 0.683
3mvw BHZNickel-binding periplasmic protein / 0.677
2z4y 252Geranylgeranyl pyrophosphate synthase / 0.675
4tl6 ANPCircadian clock protein kinase KaiC 2.7.11.1 0.671
2qc8 ADPGlutamine synthetase 6.3.1.2 0.669
1zha PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.667
4fvq ATPTyrosine-protein kinase JAK2 / 0.666
3tb9 ANPRibonucleoside-diphosphate reductase large chain 1 1.17.4.1 0.664
3ryh GTPTubulin alpha chain / 0.662
3wnz ADPAlanine--anticapsin ligase / 0.661
2opm NI9Farnesyl pyrophosphate synthase 2.5.1.10 0.660
4lrl DGTHD domain protein / 0.655
4zol GTPTubulin alpha-1B chain / 0.655
3dt4 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.654
3m0e ATPTranscriptional regulator (NtrC family) / 0.652
5ero 210Fusicoccadiene synthase 2.5.1.29 0.650