sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2nq8 | ZID | Enoyl-ACP reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2nq8 | ZID | Enoyl-ACP reductase | / | 1.132 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.892 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.806 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.793 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.751 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.742 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.733 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.730 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.729 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.727 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.725 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.721 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.711 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.704 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.704 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.701 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.699 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.699 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.697 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.697 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.696 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.693 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.688 | |
| 4clo | NAP | Pteridine reductase | / | 0.688 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.684 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.684 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.682 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.680 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.679 | |
| 1sny | NAP | LD36273p | / | 0.678 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.678 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.677 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.675 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.672 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.670 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.670 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.670 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.669 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.669 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.669 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.668 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.667 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.666 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.666 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.666 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.666 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.663 | |
| 4kwh | NAP | Reductase homolog | / | 0.662 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.661 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.660 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.658 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.658 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.658 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.657 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.656 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.656 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.655 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.654 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.652 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.651 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.650 |