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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2jgb MGT Eukaryotic translation initiation factor 4E type 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2jgb MGTEukaryotic translation initiation factor 4E type 2 / 1.025
4aza MGOEukaryotic translation initiation factor 4E / 0.682
4nv0 MG77-methylguanosine phosphate-specific 5'-nucleotidase / 0.679
1st0 GTGm7GpppX diphosphatase 3.6.1.59 0.667
2jj8 AZZDeoxynucleoside kinase / 0.663
3ea5 GDPGTP-binding nuclear protein Ran / 0.661
4cb6 29RPolymerase basic protein 2 / 0.658
4n49 MGTCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 2.1.1.57 0.652
2vqz MGTPolymerase basic protein 2 / 0.651
3onw GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.650