Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2j50 627 Aurora kinase A 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2j50 627Aurora kinase A 2.7.11.1 0.884
2xba 571ALK tyrosine kinase receptor 2.7.10.1 0.779
2v7a 627Tyrosine-protein kinase ABL1 2.7.10.2 0.745
2bmc MPYAurora kinase A 2.7.11.1 0.693
2j4z 626Aurora kinase A 2.7.11.1 0.687
1vyw 292Cyclin-dependent kinase 2 2.7.11.22 0.659
3w16 P9JAurora kinase A 2.7.11.1 0.656
4f63 0S7Fibroblast growth factor receptor 1 / 0.655
3lfs A07Cyclin-dependent kinase 2 2.7.11.22 0.653
2c4g 514Cyclin-dependent kinase 2 2.7.11.22 0.652
4fkj 11KCyclin-dependent kinase 2 2.7.11.22 0.651