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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2izg BTN Streptavidin

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2izg BTNStreptavidin / 1.033
2rtg BTNStreptavidin / 1.028
2rtd BTNStreptavidin / 1.027
2rtf BTNStreptavidin / 1.027
2izf BTNStreptavidin / 1.025
2rte BTNStreptavidin / 1.024
2y3f BTNStreptavidin / 1.010
3ry2 BTNStreptavidin / 1.008
1nqm BTNStreptavidin / 1.004
2izj BTNStreptavidin / 1.002
3wyq BTNStreptavidin / 0.994
1n9m BTNStreptavidin / 0.972
3wyp BSOStreptavidin / 0.964
1i9h BNIStreptavidin / 0.961
1mk5 BTNStreptavidin / 0.961
4gda BTNStreptavidin / 0.960
2izi BTNStreptavidin / 0.959
3rdo BTNStreptavidin / 0.950
4dne DTBStreptavidin / 0.949
4gd9 BTNStreptavidin / 0.940
2zsc BTNTamavidin2 / 0.933
1n43 BTNStreptavidin / 0.932
3wzn BTNStreptavidin / 0.929
1lcw SHMStreptavidin / 0.925
1swe BTNStreptavidin / 0.913
3rdq DTBStreptavidin / 0.906
1ndj BTNStreptavidin / 0.881
2c4i BTNAvidin / 0.880
1luq BTNStreptavidin / 0.879
1stp BTNStreptavidin / 0.879
1y52 BTNAvidin-related protein 4/5 / 0.877
2fhl BNIAvidin-related protein 4/5 / 0.875
2fhn BNIAvidin-related protein 4/5 / 0.873
4yvb BTNStreptavidin / 0.872
2rtp IMIStreptavidin / 0.870
1mep BTNStreptavidin / 0.869
1swr BTNStreptavidin / 0.865
3ew2 BTNHypothetical conserved protein / 0.865
2uyw BTNAvd protein / 0.861
2rtr IMIStreptavidin / 0.857
1swp BTNStreptavidin / 0.855
4bcs BTNAvidin-related protein 4/5 / 0.855
4z28 BTNHoefavidin / 0.853
2rto IMIStreptavidin / 0.852
1rxh BNIStreptavidin / 0.846
3t2w BTNAvidin/streptavidin / 0.843
1lcz BH7Streptavidin / 0.841
1swg BTNStreptavidin / 0.840
1swt BTNStreptavidin / 0.840
1swn BTNStreptavidin / 0.837
4bj8 BTNAvidin / 0.835
1rxj BNIStreptavidin / 0.831
2rtq IMIStreptavidin / 0.796
3vgw NVZAvidin / 0.791
1swp BTQStreptavidin / 0.789
2rtn IMIStreptavidin / 0.787
2rtl IMIStreptavidin / 0.777
3vhi VHIAvidin / 0.766
2jgs BTNAvidin / 0.761
2uz2 BTNAvd protein / 0.751
1swd BTNStreptavidin / 0.750
2izh BTNStreptavidin / 0.748
1avd BTNAvidin / 0.702
4ggz BTNBll1558 protein / 0.702
3vhh VHHAvidin / 0.693
3vhm NPKAvidin / 0.690
2rti GLLStreptavidin / 0.680
2rtk GLLStreptavidin / 0.672
1df8 BTNStreptavidin / 0.664
2avi BTNAvidin / 0.659