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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2i19 1BY Farnesyl pyrophosphate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
2i19 1BYFarnesyl pyrophosphate synthase / 0.922
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.788
4q23 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.776
4h5e YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.750
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.748
3ldw ZOLFarnesyl pyrophosphate synthase, putative / 0.741
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.741
3rbm B73Farnesyl pyrophosphate synthase, putative / 0.739
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.733
2e8w IPEGeranylgeranyl pyrophosphate synthase / 0.725
4dxj 0M9Farnesyl pyrophosphate synthase / 0.709
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.709
4dwb 0M7Farnesyl pyrophosphate synthase / 0.706
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.703
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.689
2z52 H23Geranylgeranyl pyrophosphate synthase / 0.688
2z4w 749Geranylgeranyl pyrophosphate synthase / 0.678
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.677
3krf DSTGeranyl diphosphate synthase large subunit / 0.672
3ryw K9HFarnesyl pyrophosphate synthase, putative / 0.666
1rqj RISFarnesyl diphosphate synthase 2.5.1.10 0.663
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.659
4ffl ADPUncharacterized protein / 0.651