Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2hu2 NAD C-terminal binding protein 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2hu2 NADC-terminal binding protein 1 / 1.066
1hku NADC-terminal-binding protein 1 1.1.1 0.824
4lcj NADC-terminal-binding protein 2 / 0.798
2ome NADC-terminal-binding protein 2 / 0.754
3oet NADErythronate-4-phosphate dehydrogenase / 0.751
1dxy NADD-2-hydroxyisocaproate dehydrogenase 1.1.1 0.750
1psd NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.739
1j49 NADD-lactate dehydrogenase 1.1.1.28 0.727
2g76 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.722
3kb6 NADD-lactate dehydrogenase / 0.722
1uxk NADMalate dehydrogenase / 0.720
2o4c NADErythronate-4-phosphate dehydrogenase / 0.719
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.711
4z0p NDPNAD-dependent dehydrogenase / 0.711
4dl9 NADS-(hydroxymethyl)glutathione dehydrogenase / 0.703
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.699
4weq NAPNAD-dependent dehydrogenase / 0.698
1la2 NADInositol-3-phosphate synthase 5.5.1.4 0.695
3wsw NADL-lactate dehydrogenase / 0.695
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.694
5bqf NAPProbable hydroxyacid dehydrogenase protein / 0.693
1dss NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.692
1yba NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.691
1ywg NADGlyceraldehyde-3-phosphate dehydrogenase / 0.691
4nd3 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.689
2gsd NADFormate dehydrogenase / 0.685
1h2h NADL-aspartate dehydrogenase 1.4.1.21 0.680
2aa3 AP0L-lactate dehydrogenase / 0.679
2ekl NADD-3-phosphoglycerate dehydrogenase / 0.677
2oxi NADAlcohol dehydrogenase E chain 1.1.1.1 0.676
4e5k NADPhosphonate dehydrogenase 1.20.1.1 0.676
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.675
3ec7 NADInositol 2-dehydrogenase / 0.675
1j0x NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.673
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.673
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.672
1t2c NAIL-lactate dehydrogenase 1.1.1.27 0.672
5c7o NADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific 1.2.1.12 0.672
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.671
1het NADAlcohol dehydrogenase E chain 1.1.1.1 0.670
1sow NADL-lactate dehydrogenase 1.1.1.27 0.669
2vhw NAIAlanine dehydrogenase 1.4.1.1 0.669
1c1d NAIPhenylalanine dehydrogenase / 0.666
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.666
2dc1 NADProbable L-aspartate dehydrogenase / 0.666
3had NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.666
4k9d NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.666
1e3l NADAlcohol dehydrogenase 4 1.1.1.1 0.665
6adh NADAlcohol dehydrogenase E chain 1.1.1.1 0.665
1bw9 NADPhenylalanine dehydrogenase / 0.664
1jki NAIInositol-3-phosphate synthase 5.5.1.4 0.664
2qg4 NADUDP-glucose 6-dehydrogenase 1.1.1.22 0.664
1gv0 NADMalate dehydrogenase / 0.662
1p1h NADInositol-3-phosphate synthase 5.5.1.4 0.662
1pjc NADAlanine dehydrogenase / 0.661
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.661
1p1i NADInositol-3-phosphate synthase 5.5.1.4 0.660
4e5n NADPhosphonate dehydrogenase 1.20.1.1 0.660
1hdz NADAlcohol dehydrogenase 1B 1.1.1.1 0.659
1pl6 NADSorbitol dehydrogenase 1.1.1.14 0.658
3cps NADGlyceraldehyde-3-phosphate dehydrogenase / 0.658
2pa3 NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.657
3cif NADGlyceraldehyde-3-phosphate dehydrogenase / 0.656
3ggo NAIPrephenate dehydrogenase / 0.656
4xrg NADHomospermidine synthase 2.5.1.44 0.656
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.655
3pqf NADL-lactate dehydrogenase 1.1.1.27 0.655
4o59 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.655
5dt9 NADErythronate-4-phosphate dehydrogenase / 0.655
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.654
4njo NADD-3-phosphoglycerate dehydrogenase, putative / 0.654
4xq9 NADHomospermidine synthase 2.5.1.44 0.654
1ib6 NADMalate dehydrogenase / 0.653
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.653
3nt2 NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.652
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.652
1f8f NADBenzyl alcohol dehydrogenase / 0.651
2a92 NAIL-lactate dehydrogenase / 0.651
2w2l NADD-mandelate dehydrogenase / 0.651
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.651
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.651
2dfv NADL-threonine 3-dehydrogenase / 0.650