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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2hmy SAM Modification methylase HhaI 2.1.1.37

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2hmy SAMModification methylase HhaI 2.1.1.37 0.891
2uyh SAHModification methylase HhaI 2.1.1.37 0.765
2c7q SAHModification methylase HhaI 2.1.1.37 0.762
1skm SAHModification methylase HhaI 2.1.1.37 0.760
2i9k SAHModification methylase HhaI 2.1.1.37 0.759
2z6u SAHModification methylase HhaI 2.1.1.37 0.759
9mht SAHModification methylase HhaI 2.1.1.37 0.749
2zcj SAHModification methylase HhaI 2.1.1.37 0.748
7mht SAHModification methylase HhaI 2.1.1.37 0.746
5mht SAHModification methylase HhaI 2.1.1.37 0.732
10mh SAHModification methylase HhaI 2.1.1.37 0.730
1fjx SAHModification methylase HhaI 2.1.1.37 0.725
3mht SAHModification methylase HhaI 2.1.1.37 0.725
1mht SAHModification methylase HhaI 2.1.1.37 0.720
8mht SAHModification methylase HhaI 2.1.1.37 0.703
4mht SAHModification methylase HhaI 2.1.1.37 0.693
4u7t SAHDNA (cytosine-5)-methyltransferase 3A 2.1.1.37 0.691
4dkj SAHCytosine-specific methyltransferase / 0.685
5e8j SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.680
1wg8 SAMRibosomal RNA small subunit methyltransferase H / 0.677
2f8l SAMLmo1582 protein / 0.677
3bgv SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.675
3epp SFGmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.674
3qv2 SAH5-cytosine DNA methyltransferase / 0.673
3ldg SAHUncharacterized protein / 0.670
5e9w SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.664
3a27 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.662
3a25 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.661
4yv2 S4MSpermidine synthase, putative / 0.661
1z3c SA8mRNA cap guanine-N7 methyltransferase 2.1.1.56 0.658
5il1 SAMN6-adenosine-methyltransferase 70 kDa subunit / 0.657
2zif SAMMethyltransferase / 0.655
4yv1 S4MSpermidine synthase, putative / 0.650