Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2gqg 1N1 Tyrosine-protein kinase ABL1 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2gqg 1N1Tyrosine-protein kinase ABL1 2.7.10.2 1.061
4xey 1N1Tyrosine-protein kinase ABL1 2.7.10.2 0.947
2zva 1N1Tyrosine-protein kinase Lyn 2.7.10.2 0.912
3qlg 1N1Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.839
4xli 1N1Abelson tyrosine-protein kinase 2 2.7.10.2 0.834
3bx5 304Mitogen-activated protein kinase 14 / 0.750
2y6o 1N1Ephrin type-A receptor 4 2.7.10.1 0.728
2zm1 KSFTyrosine-protein kinase Lck 2.7.10.2 0.727
4kip 1R9Mitogen-activated protein kinase 14 / 0.724
2g2h P16Tyrosine-protein kinase ABL1 2.7.10.2 0.717
3oct 1N1Tyrosine-protein kinase BTK 2.7.10.2 0.710
3ocg OCGMitogen-activated protein kinase 14 / 0.703
3l8x N4DMitogen-activated protein kinase 14 / 0.699
3gfe P37Mitogen-activated protein kinase 14 / 0.690
3itz P66Mitogen-activated protein kinase 14 / 0.689
2bdj HETProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.681
2zm4 KSMTyrosine-protein kinase Lck 2.7.10.2 0.680
4kin 1M8Mitogen-activated protein kinase 14 / 0.679
5bvw 1N1Epithelial discoidin domain-containing receptor 1 2.7.10.1 0.664
4eh6 0ONMitogen-activated protein kinase 14 / 0.658
4mxo DB8Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.657
3b2w 9NHTyrosine-protein kinase Lck 2.7.10.2 0.656
2hzi JINTyrosine-protein kinase ABL1 2.7.10.2 0.650