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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2g6p HM2 Methionine aminopeptidase 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2g6p HM2Methionine aminopeptidase 1 / 0.830
4iku SHXMethionine aminopeptidase 1 / 0.785
4ikr PVPMethionine aminopeptidase 1 / 0.759
4ikt TFVMethionine aminopeptidase 1 / 0.755
4iks TFDMethionine aminopeptidase 1 / 0.748
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.691
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.691
2zue ANPArginine--tRNA ligase 6.1.1.19 0.691
3uxv GUNNADPH-dependent 7-cyano-7-deazaguanine reductase / 0.691
4iok ADPFormate--tetrahydrofolate ligase / 0.691
4jjz ADPFormate--tetrahydrofolate ligase / 0.691
4y8v ADPAcyl-CoA synthetase (NDP forming) / 0.691