sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2g5o | DRQ | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2g5o | DRQ | Estrogen receptor | / | 1.253 | |
| 2yja | EST | Estrogen receptor | / | 1.008 | |
| 3oll | EST | Estrogen receptor beta | / | 0.984 | |
| 5hyr | EST | Estrogen receptor | / | 0.973 | |
| 3uud | EST | Estrogen receptor | / | 0.962 | |
| 2j7x | EST | Estrogen receptor beta | / | 0.957 | |
| 5dxg | EST | Estrogen receptor | / | 0.937 | |
| 5dx3 | EST | Estrogen receptor | / | 0.933 | |
| 2qgt | EED | Estrogen receptor | / | 0.922 | |
| 2yat | EEU | Estrogen receptor | / | 0.919 | |
| 1gwr | EST | Estrogen receptor | / | 0.894 | |
| 4pxm | EST | Estrogen receptor | / | 0.890 | |
| 2ocf | EST | Estrogen receptor | / | 0.874 | |
| 1g50 | EST | Estrogen receptor | / | 0.871 | |
| 3ols | EST | Estrogen receptor beta | / | 0.869 | |
| 3q95 | ESL | Estrogen receptor | / | 0.851 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.838 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.834 | |
| 4e5i | 0N9 | Polymerase acidic protein | / | 0.744 | |
| 2fai | 459 | Estrogen receptor | / | 0.731 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.716 | |
| 4pp6 | STL | Estrogen receptor | / | 0.714 | |
| 1u9e | 397 | Estrogen receptor beta | / | 0.712 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.703 | |
| 2piu | DHT | Androgen receptor | / | 0.696 | |
| 2b1z | 17M | Estrogen receptor | / | 0.694 | |
| 1x7e | 244 | Estrogen receptor | / | 0.692 | |
| 1lho | AOM | Sex hormone-binding globulin | / | 0.686 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.684 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.684 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.683 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.681 | |
| 2qa8 | GEN | Estrogen receptor | / | 0.679 | |
| 1ogx | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.677 | |
| 1qkm | GEN | Estrogen receptor beta | / | 0.677 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.677 | |
| 4ofr | DHT | Androgen receptor | / | 0.674 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.671 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.668 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.666 | |
| 1x76 | 697 | Estrogen receptor beta | / | 0.663 | |
| 2piw | DHT | Androgen receptor | / | 0.663 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.663 | |
| 2pit | DHT | Androgen receptor | / | 0.661 | |
| 4oey | DHT | Androgen receptor | / | 0.661 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.660 | |
| 4e5f | 0N7 | Polymerase acidic protein | / | 0.660 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.659 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.659 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.658 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.656 | |
| 4e5l | DBH | Polymerase acidic protein | / | 0.655 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.652 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.651 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.650 |