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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2g2f AGS Tyrosine-protein kinase ABL1 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2g2f AGSTyrosine-protein kinase ABL1 2.7.10.2 0.798
4xlv ACPInsulin receptor 2.7.10.1 0.677
3uim ANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 2.7.10.1 0.672
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.664
4cki ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.663
2xs0 ANPMitogen-activated protein kinase 8 2.7.11.24 0.661
5c1o ANPD-alanine--D-alanine ligase / 0.655
3ung ADPCRISPR system Cmr subunit Cmr2 / 0.651
4bix ADPSensor histidine kinase CpxA / 0.650
5c8y ACPTubulin tyrosine ligase / 0.650