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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2g27 4LG Renin 3.4.23.15

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
2g27 4LGRenin 3.4.23.15 1.260
2fs4 PZ1Renin 3.4.23.15 0.848
2g26 3LGRenin 3.4.23.15 0.811
2bkt RPFRenin 3.4.23.15 0.771
3g6z A7TRenin 3.4.23.15 0.719
3o9l LPNRenin 3.4.23.15 0.688
3vsw R31Renin 3.4.23.15 0.663