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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2fxs RDA ATP-dependent molecular chaperone HSP82

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2fxs RDAATP-dependent molecular chaperone HSP82 / 0.898
2iws NP4ATP-dependent molecular chaperone HSP82 / 0.816
2iwx M1SATP-dependent molecular chaperone HSP82 / 0.808
2xd6 XD6ATP-dependent molecular chaperone HSP82 / 0.798
2iwu NP5ATP-dependent molecular chaperone HSP82 / 0.789
2gfd RDAEndoplasmin / 0.787
2xx5 13NATP-dependent molecular chaperone HSP82 / 0.786
2cgf P2NATP-dependent molecular chaperone HSP82 / 0.783
2wer RDCATP-dependent molecular chaperone HSP82 / 0.772
2bre KJ2ATP-dependent molecular chaperone HSP82 / 0.769
4ce1 7FKATP-dependent molecular chaperone HSP82 / 0.749
4e5i 0N9Polymerase acidic protein / 0.744
1u0z RDCEndoplasmin / 0.739
2xx4 13IATP-dependent molecular chaperone HSP82 / 0.730
1bgq RDCATP-dependent molecular chaperone HSP82 / 0.728
4ce2 BO5ATP-dependent molecular chaperone HSP82 / 0.727
1qy8 RDIEndoplasmin / 0.722
2xx2 13CATP-dependent molecular chaperone HSP82 / 0.703
2brc CT5ATP-dependent molecular chaperone HSP82 / 0.695
4egk RDCHeat shock protein HSP 90-alpha / 0.671
1yc4 43PHeat shock protein HSP 90-alpha / 0.668
3eko PYUHeat shock protein HSP 90-alpha / 0.667
2fyp RDEEndoplasmin / 0.665
2bz5 AB4Heat shock protein HSP 90-alpha / 0.656