Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2fk8 SAM Hydroxymycolate synthase MmaA4 2.1.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2fk8 SAMHydroxymycolate synthase MmaA4 2.1.1 0.967
1kph SAHCyclopropane mycolic acid synthase 1 2.1.1.79 0.861
3ha5 SFGHydroxymycolate synthase MmaA4 2.1.1 0.826
3ha3 SAHHydroxymycolate synthase MmaA4 2.1.1 0.797
4pne SAHMethyltransferase-like protein / 0.719
1f3l SAHProtein arginine N-methyltransferase 3 / 0.707
3dlc SAMSAM (And some other nucleotide) binding motif:Generic methyltransferase / 0.697
5e8j SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.697
3vc1 SAHGeranyl diphosphate 2-C-methyltransferase 2.1.1.255 0.696
5dx8 SFGHistone-arginine methyltransferase CARM1 / 0.695
5dwq SFGHistone-arginine methyltransferase CARM1 / 0.689
2y1w SFGHistone-arginine methyltransferase CARM1 / 0.686
3vc2 SAHGeranyl diphosphate 2-C-methyltransferase 2.1.1.255 0.684
3b3f SAHHistone-arginine methyltransferase CARM1 / 0.682
5dx1 SFGHistone-arginine methyltransferase CARM1 / 0.680
5dxj SFGHistone-arginine methyltransferase CARM1 / 0.675
2xvm SAHTellurite methyltransferase 2.1.1.265 0.669
3g8a SAHRibosomal RNA small subunit methyltransferase G / 0.669
4lwp SAHArginine N-methyltransferase, putative / 0.669
2yqz SAMUncharacterized protein / 0.663
4qpp SAHProtein arginine N-methyltransferase 6 / 0.662
1z3c SA8mRNA cap guanine-N7 methyltransferase 2.1.1.56 0.657
4gqb 0XUProtein arginine N-methyltransferase 5 / 0.657
5icf SAH(S)-norcoclaurine 6-O-methyltransferase / 0.656
2a14 SAHIndolethylamine N-methyltransferase 2.1.1.49 0.655
2i62 SAHNicotinamide N-methyltransferase 2.1.1.1 0.654
3epp SFGmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.654
5f2k SAHUncharacterized protein / 0.653
3a27 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.652
3a4t SFGtRNA (cytosine(48)-C(5))-methyltransferase 2.1.1 0.651
2p35 SAHTrans-aconitate 2-methyltransferase / 0.650