sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 1.496 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 1.348 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.321 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.300 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.297 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.280 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.272 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 1.267 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 1.250 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.241 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.217 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 1.199 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 1.182 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 1.177 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.160 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 1.158 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.156 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 1.148 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 1.147 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.140 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 1.133 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.131 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.129 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 1.117 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.116 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.105 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.100 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.099 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 1.084 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.078 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 1.071 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.071 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.067 | |
| 2wow | FAD | Trypanothione reductase | / | 1.066 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.056 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.053 | |
| 2r9z | FAD | Glutathione amide reductase | / | 1.052 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.048 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 1.044 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.040 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.040 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.037 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.036 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 1.034 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 1.031 | |
| 2jk6 | FAD | Trypanothione reductase | / | 1.030 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.020 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.020 | |
| 4nev | FAD | Trypanothione reductase | / | 1.015 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.008 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.005 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.002 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.998 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.998 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.998 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.995 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.993 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.992 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.977 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.976 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.973 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.970 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.969 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.965 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.963 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.958 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.950 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.947 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.947 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.946 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.943 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.943 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.940 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.934 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.930 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.928 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.921 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.915 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.912 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.909 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.906 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.899 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.898 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.894 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.893 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.893 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.890 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.886 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.882 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.880 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.878 | |
| 4nte | FAD | DepH | / | 0.875 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.874 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.872 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.868 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.866 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.864 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.863 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.861 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.857 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.856 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.854 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.849 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.848 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.847 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.840 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.838 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.834 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.832 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.831 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.831 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.830 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.829 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.829 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.828 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.828 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.827 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.826 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.826 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.825 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.825 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.824 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.824 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.822 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.822 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.822 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.822 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.822 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.820 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.819 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.818 | |
| 2qa1 | FAD | PgaE | / | 0.812 | |
| 3fbs | FAD | Oxidoreductase | / | 0.812 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.812 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.811 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.810 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.807 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.807 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.805 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.804 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.804 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.801 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.801 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.800 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.800 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.799 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.795 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.792 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.791 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.791 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.790 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.790 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.790 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.789 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.789 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.787 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.787 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.785 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.784 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.783 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.783 | |
| 4x4j | FAD | Putative oxygenase | / | 0.783 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.779 | |
| 4jn9 | FAD | DepH | / | 0.779 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.777 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.777 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.777 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.776 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.776 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.774 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.774 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.774 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.773 | |
| 4tm3 | FAD | KtzI | / | 0.772 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.772 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.771 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.771 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.770 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.770 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.769 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.769 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.767 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.767 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.766 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.765 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.765 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.764 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.763 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.762 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.761 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.761 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.760 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.760 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.759 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.757 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.757 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.755 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.755 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.755 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.753 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.752 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.751 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.750 | |
| 4k5r | FAD | Oxygenase | / | 0.750 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.749 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.747 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.747 | |
| 4tlz | FAD | KtzI | / | 0.747 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.746 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.745 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.744 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.744 | |
| 2bab | FAD | Putative aminooxidase | / | 0.743 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.742 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.742 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.741 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.740 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.738 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.737 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.737 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.736 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.736 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.736 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.735 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.735 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.735 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.734 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.734 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.733 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.733 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.733 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.732 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.730 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.730 | |
| 2bac | FAD | Putative aminooxidase | / | 0.729 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.729 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.729 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.728 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.728 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.728 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.728 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.728 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.728 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.727 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.727 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.726 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.726 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.726 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.725 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.725 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.724 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.724 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.724 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.724 | |
| 3rha | FDA | Putrescine oxidase | / | 0.724 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.724 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.724 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.723 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.722 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.722 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.722 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.722 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.721 | |
| 2cul | FAD | GidA-related protein | / | 0.721 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.721 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.721 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.721 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.720 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.719 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.719 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.719 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.719 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.719 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.719 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.719 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.719 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.718 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.718 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.717 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.717 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.717 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.716 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.716 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.716 | |
| 2yvj | FAD | Ferredoxin reductase | / | 0.714 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.713 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.713 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.712 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.712 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.712 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.711 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.711 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.710 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.710 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.709 | |
| 3fmw | FAD | Oxygenase | / | 0.709 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.709 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.709 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.709 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.708 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.707 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.707 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.707 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.706 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.706 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.705 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.704 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.704 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.704 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.704 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.703 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.702 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.701 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.701 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.701 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.701 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.700 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.700 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.700 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.699 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.699 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.698 | |
| 4tm1 | FDA | KtzI | / | 0.698 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.697 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.697 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.697 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.697 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.697 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.696 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.696 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.695 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.695 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.694 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.694 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.693 | |
| 1y56 | ATP | Uncharacterized protein | / | 0.693 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.692 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.691 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.691 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.691 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.691 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.691 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.690 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.690 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.690 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.690 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.690 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.689 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.689 | |
| 1pkv | RBF | Riboflavin synthase | 2.5.1.9 | 0.688 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.688 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.688 | |
| 4ap1 | FAD | Steroid monooxygenase | / | 0.688 | |
| 4icy | FAD | PgaE | / | 0.688 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.688 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.687 | |
| 4ysh | FAD | Glycine oxidase | / | 0.687 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.686 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.686 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.686 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.686 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.686 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.685 | |
| 4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.685 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.685 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.685 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.684 | |
| 2qcu | FAD | Aerobic glycerol-3-phosphate dehydrogenase | 1.1.5.3 | 0.684 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.684 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.684 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.683 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.683 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.683 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.683 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.682 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.682 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.682 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.682 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.682 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.681 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.681 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.681 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.681 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.680 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.680 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.679 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.678 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.678 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.678 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.678 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.678 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.677 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.677 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.677 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.677 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.677 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.677 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.677 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.676 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.676 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.674 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.674 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.674 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.674 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.674 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.673 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.673 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.673 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.672 | |
| 2cdu | FAD | NADH oxidase | / | 0.672 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.672 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.671 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.671 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.670 | |
| 3qj4 | FAD | Renalase | / | 0.670 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.669 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.669 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.668 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.668 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.668 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.668 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.668 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.667 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.667 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.667 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.666 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.666 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.665 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.665 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.664 | |
| 4tm4 | FDA | KtzI | / | 0.664 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.663 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.663 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.662 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.662 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.662 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.662 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.662 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.662 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.662 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.661 | |
| 1n9n | FMN | Putative blue light receptor | / | 0.661 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.660 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.660 | |
| 3d72 | FAD | Vivid PAS protein VVD | / | 0.660 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.660 | |
| 2ed4 | FAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.659 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.659 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.659 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.659 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.659 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.658 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.658 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.658 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.657 | |
| 3bnk | FMN | Flavoredoxin | / | 0.657 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.657 | |
| 4tm0 | FAD | KtzI | / | 0.657 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.657 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.657 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.656 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.656 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.656 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.656 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.655 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.655 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.655 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.655 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.655 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.655 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.654 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.654 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.653 | |
| 2o07 | MTA | Spermidine synthase | 2.5.1.16 | 0.653 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.653 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.652 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.652 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.652 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.651 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.651 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.651 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.650 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.650 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.650 |