Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2d4v NAD Isocitrate dehydrogenase [NADP]

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2d4v NADIsocitrate dehydrogenase [NADP] / 1.170
1xkd NAPIsocitrate dehydrogenase [NADP] / 0.857
4f7i NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.838
4xxv NAD3-isopropylmalate dehydrogenase / 0.838
2cmj NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.817
3flk NAITartrate dehydrogenase/decarboxylase 1.1.1.93 0.815
2d1c NAPIsocitrate dehydrogenase [NADP] 1.1.1.42 0.789
2cmv NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.773
4wuo NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.740
4kzo NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.737
2y42 NAD3-isopropylmalate dehydrogenase 1.1.1.85 0.731
4umx NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.731
3inm NDPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.730
4umy NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.724
4aov NAPIsocitrate dehydrogenase [NADP] / 0.716
4l06 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.696
4l04 NAPIsocitrate dehydrogenase [NADP] cytoplasmic 1.1.1.42 0.680
2r5t ANPSerine/threonine-protein kinase Sgk1 2.7.11.1 0.659
2yy5 WSATryptophan--tRNA ligase 6.1.1.2 0.654