Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2c68 CT6 Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2c68 CT6Cyclin-dependent kinase 2 2.7.11.22 0.915
2c69 CT8Cyclin-dependent kinase 2 2.7.11.22 0.836
2r3f SC8Cyclin-dependent kinase 2 2.7.11.22 0.762
2r3i SCFCyclin-dependent kinase 2 2.7.11.22 0.727
2r3k SCQCyclin-dependent kinase 2 2.7.11.22 0.712
2r3q 5SCCyclin-dependent kinase 2 2.7.11.22 0.708
2r3p 3SCCyclin-dependent kinase 2 2.7.11.22 0.689
2c6i DT1Cyclin-dependent kinase 2 2.7.11.22 0.669
1unl RRCCyclin-dependent-like kinase 5 2.7.11.1 0.662
3pj8 404Cyclin-dependent kinase 2 2.7.11.22 0.659
1w8c N69Cyclin-dependent kinase 2 2.7.11.22 0.658
1y8y CT7Cyclin-dependent kinase 2 2.7.11.22 0.657