Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2bp1 NDP Aflatoxin B1 aldehyde reductase member 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2bp1 NDPAflatoxin B1 aldehyde reductase member 2 / 1.464
2c91 NAPAflatoxin B1 aldehyde reductase member 2 / 1.220
1gve NAPAflatoxin B1 aldehyde reductase member 3 1 1.174
2clp NDPAflatoxin B1 aldehyde reductase member 3 / 1.149
1lqa NDPProtein tas / 0.938
1mi3 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.814
2r9r NAPVoltage-gated potassium channel subunit beta-2 / 0.808
4jta NAPVoltage-gated potassium channel subunit beta-2 / 0.805
2acq NAPAldose reductase 1.1.1.21 0.799
1x98 NAPAldose reductase 1.1.1.21 0.792
4jq3 NAPAldo-keto reductase family 1 member C2 / 0.781
1k8c NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.779
1x96 NAPAldose reductase 1.1.1.21 0.777
3lut NAPVoltage-gated potassium channel subunit beta-2 / 0.776
1ads NAPAldose reductase 1.1.1.21 0.763
1ye4 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.762
3lnm NAPVoltage-gated potassium channel subunit beta-2 / 0.758
1ye6 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.756
1sm9 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.755
4jtd NAPVoltage-gated potassium channel subunit beta-2 / 0.754
1r38 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.753
3g1r NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.748
3dop NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.746
5c7h NDPPutative oxidoreductase / 0.745
3uzw NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.738
1ye6 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.725
4pmj NAPPutative oxidoreductase / 0.721
2j8t NAPAldose reductase 1.1.1.21 0.713
3bv7 NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.711
2fvl NAPAldo-keto reductase family 1 member C4 1.1.1.225 0.709
1z8a NAPAldose reductase 1.1.1.21 0.708
4aub NAPL-glyceraldehyde 3-phosphate reductase 1.1.1 0.708
2pfh NDPAldose reductase 1.1.1.21 0.706
2pev NDPAldose reductase 1.1.1.21 0.702
2pf8 NDPAldose reductase 1.1.1.21 0.702
3buv NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.702
1s1r NAPAldo-keto reductase family 1 member C3 / 0.701
3v36 NAPAldose reductase 1.1.1.21 0.701
1lwi NAP3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.694
3q67 NAPAldose reductase 1.1.1.21 0.693
2acu NAPAldose reductase 1.1.1.21 0.689
3q65 NAPAldose reductase 1.1.1.21 0.689
4g5d NDPProstaglandin F synthase 1.1.1.188 0.687
3h7r NAPAldo-keto reductase family 4 member C8 / 0.686
1qrq NDPVoltage-gated potassium channel subunit beta-2 / 0.682
2he5 NDPAldo-keto reductase family 1 member C21 1.1.1 0.682
4jtc NAPVoltage-gated potassium channel subunit beta-2 / 0.678
1s1p NAPAldo-keto reductase family 1 member C3 / 0.675
2bgs NDPAldose reductase 1.1.1.21 0.674
2iq0 NAPAldose reductase 1.1.1.21 0.674
1z9a NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.673
1giq NAIIota toxin component Ia / 0.666
3ln3 NADAldo-keto reductase family 1 member C13 / 0.666
2acs NAPAldose reductase 1.1.1.21 0.664
4a1o AMZBifunctional purine biosynthesis protein PurH 2.1.2.3 0.662
1og6 NAPOxidoreductase YdhF 1 0.661
4dz5 NAPAldo-keto reductase family 1 member C3 / 0.660
2eer NADNAD-dependent alcohol dehydrogenase 1.1.1.1 0.659
3caq NDP3-oxo-5-beta-steroid 4-dehydrogenase / 0.659
3h7u NAPNADPH-dependent aldo-keto reductase, chloroplastic / 0.658
4ijr NDPD-arabinose dehydrogenase [NAD(P)+] heavy chain 1.1.1.117 0.658
4xo7 NAPAldo-keto reductase family 1 member C2 / 0.658
1uuo BRFDihydroorotate dehydrogenase (quinone), mitochondrial 1.3.5.2 0.654
1zgd NAPChalcone reductase / 0.653
3zcb ATPAdenosine monophosphate-protein transferase VbhT 2.7.7.n1 0.653
1q5m NDPProstaglandin-E(2) 9-reductase 1.1.1.189 0.652