Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2blb CP7 Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2blb CP7Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.894
2bl9 CP6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.781
2blc CP7Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.765
1j3j CP6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.759
3qg2 CP6Bifunctional dihydrofolate reductase-thymidylate synthase / 0.754
2bla CP6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.738
3um5 CP6Bifunctional dihydrofolate reductase-thymidylate synthase / 0.719
3qgt CP6Bifunctional dihydrofolate reductase-thymidylate synthase / 0.709
3qlz QLZUncharacterized protein / 0.702
3qfx CP6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.676
4h98 14QUncharacterized protein / 0.676
4kd7 9DRDihydrofolate reductase 1.5.1.3 0.670
1ia2 TQ4Dihydrofolate reductase 1.5.1.3 0.668
1m79 MQ1Dihydrofolate reductase 1.5.1.3 0.659
4h95 06UDihydrofolate reductase 1.5.1.3 0.659
4ixf IXFDihydrofolate reductase 1.5.1.3 0.654
3nxo D2BDihydrofolate reductase 1.5.1.3 0.653
3qlx QLRUncharacterized protein / 0.653
3sr5 Q12Dihydrofolate reductase 1.5.1.3 0.653