Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2bfy H1N Aurora kinase B-A 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2bfy H1NAurora kinase B-A 2.7.11.1 1.031
4qmt H1NSerine/threonine-protein kinase 24 2.7.11.1 0.709
3c7q XINVascular endothelial growth factor receptor 2 2.7.10.1 0.707
2pe1 5173-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.690
4aw5 30KEphrin type-B receptor 4 2.7.10.1 0.685
2pe2 4643-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.683
3l9l L9LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.682
2x2m X2MProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.678
2x2k X2KProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.674
2wmw ZYWSerine/threonine-protein kinase Chk1 2.7.11.1 0.672
4oth DRNSerine/threonine-protein kinase N1 / 0.672
2bro DF2Serine/threonine-protein kinase Chk1 2.7.11.1 0.671
2brg DFYSerine/threonine-protein kinase Chk1 2.7.11.1 0.668
4agd B49Vascular endothelial growth factor receptor 2 2.7.10.1 0.666
3g0f B49Mast/stem cell growth factor receptor Kit 2.7.10.1 0.661
2ym3 YM3Serine/threonine-protein kinase Chk1 2.7.11.1 0.658
1unh IXMCyclin-dependent-like kinase 5 2.7.11.1 0.657
2pe0 39Z3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.657
2cgu 3A3Serine/threonine-protein kinase Chk1 2.7.11.1 0.654
2brm DFZSerine/threonine-protein kinase Chk1 2.7.11.1 0.652