sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2bac | FAD | Putative aminooxidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2bac | FAD | Putative aminooxidase | / | 1.468 | |
| 2bab | FAD | Putative aminooxidase | / | 1.407 | |
| 2b9y | FAD | Putative aminooxidase | / | 1.339 | |
| 2b9x | FAD | Putative aminooxidase | / | 1.307 | |
| 2b9w | FAD | Putative aminooxidase | / | 1.248 | |
| 2ba9 | FAD | Putative aminooxidase | / | 1.227 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.988 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.964 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.961 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.954 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.933 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.925 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.911 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.906 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.898 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.894 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.894 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.875 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.867 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.865 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.864 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.863 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.861 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.861 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.853 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.852 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.851 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.848 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.844 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.838 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.838 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.835 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.833 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.833 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.825 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.823 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.823 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.821 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.818 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.816 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.816 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.814 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.813 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.813 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.810 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.808 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.808 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.806 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.804 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.804 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.803 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.803 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.803 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.803 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.802 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.802 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.801 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.800 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.798 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.798 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.797 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.795 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.795 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.795 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.794 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.793 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.793 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.793 | |
| 3qj4 | FAD | Renalase | / | 0.793 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.792 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.792 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.792 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.791 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.791 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.791 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.787 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.786 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.786 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.784 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.784 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.783 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.781 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.781 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.781 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.781 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.780 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.779 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.778 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.778 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.776 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.775 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.773 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.773 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.773 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.772 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.772 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.770 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.770 | |
| 3rha | FDA | Putrescine oxidase | / | 0.768 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.767 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.766 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.765 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.765 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.765 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.764 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.763 | |
| 4tm1 | FDA | KtzI | / | 0.763 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.762 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.762 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.760 | |
| 1sez | FAD | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.759 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.759 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.759 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.758 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.758 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.757 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.756 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.755 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.755 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.755 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.755 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.754 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.754 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.752 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.751 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.750 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.750 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.749 | |
| 3kkj | FAD | Renalase | / | 0.748 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.748 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.748 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.746 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.746 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.745 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.745 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.745 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.745 | |
| 4nev | FAD | Trypanothione reductase | / | 0.745 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.744 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.744 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.744 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.744 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.744 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.742 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.742 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.741 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.741 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.741 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.741 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.740 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.740 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.740 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.739 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.739 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.738 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.737 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.737 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.737 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.737 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.737 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.737 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.736 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.736 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.735 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.735 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.735 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.735 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.734 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.734 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.734 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.733 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.733 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.732 | |
| 2wow | FAD | Trypanothione reductase | / | 0.732 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.732 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.732 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.731 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.731 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.731 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.730 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.729 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.729 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.729 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.729 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.729 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.729 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.729 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.729 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.728 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.728 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.728 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.727 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.727 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.727 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.727 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.727 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.726 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.726 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.726 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.724 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.724 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.723 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.722 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.722 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.722 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.722 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.722 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.721 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.721 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.721 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.721 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.721 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.721 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.720 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.720 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.720 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.720 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.719 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.719 | |
| 4ysh | FAD | Glycine oxidase | / | 0.719 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.718 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.718 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.718 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.717 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.716 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.716 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.716 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.716 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.715 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.715 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.715 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.715 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.715 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.715 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.715 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.714 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.714 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.713 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.713 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.713 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.713 | |
| 4tm3 | FAD | KtzI | / | 0.713 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.712 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.712 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.711 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.711 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.711 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.710 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.710 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.710 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.710 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.710 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.710 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.710 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.709 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.709 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.709 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.709 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.709 | |
| 4tm4 | FDA | KtzI | / | 0.709 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.708 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.708 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.707 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.706 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.705 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.705 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.705 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.704 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.704 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.704 | |
| 4nte | FAD | DepH | / | 0.704 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.703 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.703 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.703 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.702 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.702 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.702 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.702 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.702 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.702 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.702 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.702 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.701 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.701 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.700 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.700 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.698 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.698 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.698 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.698 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.698 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.697 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.697 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.696 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.696 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.696 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.696 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.695 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.695 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.694 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.694 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.694 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.693 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.693 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.691 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.691 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.691 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.691 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.691 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.691 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.690 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.690 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.689 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.688 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.687 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.686 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.686 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.686 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.686 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.685 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.685 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.685 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.684 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.684 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.684 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.684 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.684 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.683 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.682 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.682 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.681 | |
| 3fbs | FAD | Oxidoreductase | / | 0.681 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.681 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.680 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.680 | |
| 3hji | FAD | Vivid PAS protein VVD | / | 0.680 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.680 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.680 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.679 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.679 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.678 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.678 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.678 | |
| 4yxd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.678 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.677 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.677 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.677 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.676 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.676 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.676 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.676 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.676 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.675 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.675 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.675 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.675 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.675 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.674 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.674 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.674 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.673 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.673 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.672 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.672 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.672 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.672 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.672 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.672 | |
| 4jn9 | FAD | DepH | / | 0.672 | |
| 2qcu | FAD | Aerobic glycerol-3-phosphate dehydrogenase | 1.1.5.3 | 0.671 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.670 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.670 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.670 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.669 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.669 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.669 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.669 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.669 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.668 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.668 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.668 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.668 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.667 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.667 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.666 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.666 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.666 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.666 | |
| 3d72 | FAD | Vivid PAS protein VVD | / | 0.666 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.666 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.666 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.666 | |
| 5hhf | FDA | UDP-galactopyranose mutase | / | 0.666 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.665 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.665 | |
| 3pft | FMN | Flavin reductase | / | 0.665 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.665 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.665 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.663 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.663 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.662 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.662 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.662 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.662 | |
| 3uka | FAD | UDP-galactopyranose mutase | / | 0.661 | |
| 2e48 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.660 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.660 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.660 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.660 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.659 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.659 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.658 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.658 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.658 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.658 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.658 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.657 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.657 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.657 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.657 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.656 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.656 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.656 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.656 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.655 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.655 | |
| 1eje | FMN | Protein MTH_152 | / | 0.654 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.654 | |
| 3ukk | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 4xcx | SAH | Small RNA 2'-O-methyltransferase | / | 0.654 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.653 | |
| 2cdu | ADP | NADH oxidase | / | 0.653 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.653 | |
| 3da1 | FAD | Glycerol-3-phosphate dehydrogenase | / | 0.653 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.653 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.652 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.651 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.651 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.651 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.651 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.651 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.650 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.650 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.650 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.650 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.650 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.650 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.650 |