Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2b1p AIZ Mitogen-activated protein kinase 10 2.7.11.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2b1p AIZMitogen-activated protein kinase 10 2.7.11.24 1.210
3fi3 JK2Mitogen-activated protein kinase 10 2.7.11.24 0.920
4ag8 AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.778
3fko FKOMitogen-activated protein kinase 14 / 0.772
3fmm XI2Mitogen-activated protein kinase 14 / 0.727
3ttj JBIMitogen-activated protein kinase 10 2.7.11.24 0.725
1wbw LI4Mitogen-activated protein kinase 14 / 0.720
3fkn FKNMitogen-activated protein kinase 14 / 0.705
4l8m F46Mitogen-activated protein kinase 14 / 0.690
3fl4 FL4Mitogen-activated protein kinase 14 / 0.687
3fmn 530Mitogen-activated protein kinase 14 / 0.677
4nks 2M2Fibroblast growth factor receptor 1 / 0.677
3que 3FFMitogen-activated protein kinase 14 / 0.676
4fv9 E71Mitogen-activated protein kinase 1 2.7.11.24 0.672
3iw7 IPKMitogen-activated protein kinase 14 / 0.663
1uh5 TCLEnoyl-ACP reductase / 0.662
4g3f 0WBMitogen-activated protein kinase kinase kinase 14 2.7.11.25 0.658
2o2u 738Mitogen-activated protein kinase 10 2.7.11.24 0.657
3flw FLWMitogen-activated protein kinase 14 / 0.657
4fv7 E94Mitogen-activated protein kinase 1 2.7.11.24 0.653
3vs4 VSFTyrosine-protein kinase HCK 2.7.10.2 0.652
4eh7 0OOMitogen-activated protein kinase 14 / 0.651
2mm3 CHOGastrotropin / 0.650
3lfn A27Cyclin-dependent kinase 2 2.7.11.22 0.650
3thr C2FGlycine N-methyltransferase 2.1.1.20 0.650
3w32 W32Epidermal growth factor receptor 2.7.10.1 0.650