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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2b01 TUD Phospholipase A2, major isoenzyme 3.1.1.4

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2b01 TUDPhospholipase A2, major isoenzyme 3.1.1.4 1.440
2b03 TUDPhospholipase A2, major isoenzyme 3.1.1.4 0.790
3w5t LHPVitamin D3 receptor / 0.730
2b00 GCHPhospholipase A2, major isoenzyme 3.1.1.4 0.718
4ple CPSNuclear receptor subfamily 5 group A member 2 / 0.705
2piq DHTAndrogen receptor / 0.699
3cot STR3-oxo-5-beta-steroid 4-dehydrogenase / 0.697
3gyu DL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily / 0.694
2qo5 CHDFatty acid-binding protein 10-A, liver basic / 0.674
1zhz ERGOxysterol-binding protein homolog 4 / 0.672
3eqm ASDAromatase 1.14.14.14 0.668
3g1r FIT3-oxo-5-beta-steroid 4-dehydrogenase / 0.668
2ylo TESAndrogen receptor / 0.666
1p8d CO1Oxysterols receptor LXR-beta / 0.665
2pkl DHTAndrogen receptor / 0.664
4k7a DHTAndrogen receptor / 0.664
2piw DHTAndrogen receptor / 0.659
3zqt TESAndrogen receptor / 0.658
5l7d CLRSmoothened homolog / 0.658
1o1v TCHGastrotropin / 0.657
2ft9 CHDFatty acid-binding protein 2, liver / 0.657
4nky 3QZSteroid 17-alpha-hydroxylase/17,20 lyase / 0.657
3uzz ASD3-oxo-5-beta-steroid 4-dehydrogenase / 0.655
1lri CLRBeta-elicitin cryptogein / 0.654
3mno DEXGlucocorticoid receptor / 0.652
4k6i 9RARetinoic acid receptor RXR-alpha / 0.650