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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2a3i C0R Mineralocorticoid receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2a3i C0RMineralocorticoid receptor / 1.097
4uda DEXMineralocorticoid receptor / 0.951
2aa7 1CAMineralocorticoid receptor / 0.924
2aa5 STRMineralocorticoid receptor / 0.901
2aa6 STRMineralocorticoid receptor / 0.871
1y9r 1CAMineralocorticoid receptor / 0.849
3mnp DEXGlucocorticoid receptor / 0.842
4p6x HCYGlucocorticoid receptor / 0.799
3mno DEXGlucocorticoid receptor / 0.796
3mne DEXGlucocorticoid receptor / 0.778
1p93 DEXGlucocorticoid receptor / 0.767
1ya3 STRMineralocorticoid receptor / 0.739
4p6w MOFGlucocorticoid receptor / 0.731
1m2z DEXGlucocorticoid receptor / 0.704
1sqn NDRProgesterone receptor / 0.700
1sr7 MOFProgesterone receptor / 0.687
4udc DEXGlucocorticoid receptor / 0.687
4j6b PLOCytochrome P450 monooxygenase / 0.677
2aax PDNMineralocorticoid receptor / 0.671
2w8y 486Progesterone receptor / 0.670
2aa2 AS4Mineralocorticoid receptor / 0.659
5hgc HCYUncharacterized protein / 0.658
3zuy TCHTransporter / 0.656
3w1w CHDFerrochelatase, mitochondrial 4.99.1.1 0.654
2hrc CHDFerrochelatase, mitochondrial 4.99.1.1 0.652