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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zzl TZY Mitogen-activated protein kinase 14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
1zzl TZYMitogen-activated protein kinase 14 / 0.984
3fmm XI2Mitogen-activated protein kinase 14 / 0.797
2gtn LIEMitogen-activated protein kinase 14 / 0.738
3fl4 FL4Mitogen-activated protein kinase 14 / 0.738
3fc1 52PMitogen-activated protein kinase 14 / 0.735
1ywr LI9Mitogen-activated protein kinase 14 / 0.728
4loo SB4Mitogen-activated protein kinase 14 / 0.727
1bmk SB5Mitogen-activated protein kinase 14 / 0.723
1yw2 PGJMitogen-activated protein kinase 14 / 0.716
1ouy 094Mitogen-activated protein kinase 14 / 0.711
1bl7 SB4Mitogen-activated protein kinase 14 / 0.707
2gtm LIDMitogen-activated protein kinase 14 / 0.701
3iw6 PP0Mitogen-activated protein kinase 14 / 0.696
3roc 29AMitogen-activated protein kinase 14 / 0.685
3fln 3FNMitogen-activated protein kinase 14 / 0.684
3mpa SB2Mitogen-activated protein kinase 14 / 0.678
3fmn 530Mitogen-activated protein kinase 14 / 0.676
3kf7 L9GMitogen-activated protein kinase 14 / 0.674
3fko FKOMitogen-activated protein kinase 14 / 0.672
3fml FMLMitogen-activated protein kinase 14 / 0.672
3zs5 SB2Mitogen-activated protein kinase 14 / 0.672
2ghl LIBMitogen-activated protein kinase 14 / 0.671
3fkn FKNMitogen-activated protein kinase 14 / 0.670
4ewq MWLMitogen-activated protein kinase 14 / 0.670
4lop SB4Mitogen-activated protein kinase 14 / 0.666
3hp2 P36Mitogen-activated protein kinase 14 / 0.665
3flq 891Mitogen-activated protein kinase 14 / 0.656
3flz FLZMitogen-activated protein kinase 14 / 0.656
3fi4 FI4Mitogen-activated protein kinase 14 / 0.655