sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 1.198 | |
| 1zhy | CLR | Oxysterol-binding protein homolog 4 | / | 1.049 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.960 | |
| 1n38 | U3H | RNA-directed RNA polymerase lambda-3 | 2.7.7.48 | 0.744 | |
| 1nmd | ATP | Major actin | / | 0.744 | |
| 1wet | GUN | HTH-type transcriptional repressor PurR | / | 0.744 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.744 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.744 | |
| 2fzk | CTP | Aspartate carbamoyltransferase regulatory chain | / | 0.744 | |
| 2jey | HLO | Acetylcholinesterase | 3.1.1.7 | 0.744 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.744 | |
| 2z7q | ACP | Ribosomal protein S6 kinase alpha-1 | 2.7.11.1 | 0.744 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.744 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.744 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.744 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.744 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.744 | |
| 3u9d | ATP | Actin, alpha skeletal muscle | / | 0.744 | |
| 3ypi | PGH | Triosephosphate isomerase | 5.3.1.1 | 0.744 | |
| 3zzn | ADP | L-lactate dehydrogenase | / | 0.744 | |
| 4e5l | DBH | Polymerase acidic protein | / | 0.744 | |
| 5bnt | NAP | Aspartate-semialdehyde dehydrogenase | 1.2.1.11 | 0.744 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.718 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.694 | |
| 3q95 | ESL | Estrogen receptor | / | 0.674 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.673 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.667 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.663 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.663 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.661 | |
| 1h48 | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.660 | |
| 2hru | ADP | Phosphoribosylformylglycinamidine synthase subunit PurL | / | 0.660 | |
| 2hs4 | ACP | Phosphoribosylformylglycinamidine synthase subunit PurL | / | 0.660 | |
| 3fwy | ADP | Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | / | 0.660 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.660 | |
| 4cdg | ADP | Bloom syndrome protein | 3.6.4.12 | 0.660 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.660 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.660 | |
| 4o3m | ADP | Bloom syndrome protein | 3.6.4.12 | 0.660 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.660 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.659 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.658 | |
| 3eqm | ASD | Aromatase | 1.14.14.14 | 0.657 | |
| 4bqu | CLR | Japanin | / | 0.656 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.654 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.653 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.653 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.651 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.650 |