sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 1.227 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 1.109 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 1.073 | |
| 1qsr | ACO | HAT A1 | / | 0.902 | |
| 1pua | COA | HAT A1 | / | 0.842 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.837 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.834 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.834 | |
| 1pu9 | COA | HAT A1 | / | 0.831 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.830 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.827 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.826 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.817 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.807 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.799 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.795 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.791 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.788 | |
| 1m1d | LYX | HAT A1 | / | 0.781 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.779 | |
| 1qsn | COA | HAT A1 | / | 0.776 | |
| 2zpa | ACO | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.761 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.759 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.755 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.754 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.752 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.752 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.748 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.748 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.741 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.739 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.736 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.735 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.735 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.731 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.729 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.728 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.724 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.719 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.719 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.711 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.710 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.709 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.699 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.699 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.698 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.696 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.696 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.695 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.694 | |
| 4crz | ACO | PanD regulatory factor | / | 0.694 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.693 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.689 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.688 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.685 | |
| 4ua3 | COA | N-alpha-acetyltransferase 40 | 2.3.1 | 0.676 | |
| 4ava | ACO | Acetyltransferase Pat | 2.3.1 | 0.675 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.674 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.673 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.670 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.669 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.667 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.666 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.665 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.665 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.664 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.664 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.661 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.661 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.660 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.660 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.657 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.655 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.653 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.652 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.652 | |
| 4cry | ACO | PanD regulatory factor | / | 0.652 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.650 |