Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1y6b AAX Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1y6b AAXVascular endothelial growth factor receptor 2 2.7.10.1 1.061
1y6a AAZVascular endothelial growth factor receptor 2 2.7.10.1 0.887
3vo3 0KFVascular endothelial growth factor receptor 2 2.7.10.1 0.661
4ftt 6HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.657
3lfn A27Cyclin-dependent kinase 2 2.7.11.22 0.652
4ftr 5HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.650