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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1y6a AAZ Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1y6a AAZVascular endothelial growth factor receptor 2 2.7.10.1 0.943
1y6b AAXVascular endothelial growth factor receptor 2 2.7.10.1 0.887
4ft0 HK9Serine/threonine-protein kinase Chk1 2.7.11.1 0.677
4fsw HK6Serine/threonine-protein kinase Chk1 2.7.11.1 0.666
4af3 VX6Aurora kinase B 2.7.11.1 0.664
4ftt 6HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.658
4fsy HK7Serine/threonine-protein kinase Chk1 2.7.11.1 0.657
4f63 0S7Fibroblast growth factor receptor 1 / 0.652