Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1xj7 DHT Androgen receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1xj7 DHTAndrogen receptor / 1.142
1t74 DHTAndrogen receptor / 0.986
2pip DHTAndrogen receptor / 0.984
2pkl DHTAndrogen receptor / 0.983
1t5z DHTAndrogen receptor / 0.981
1t7r DHTAndrogen receptor / 0.977
2piw DHTAndrogen receptor / 0.976
2piq DHTAndrogen receptor / 0.970
1t79 DHTAndrogen receptor / 0.966
4oey DHTAndrogen receptor / 0.957
4oez DHTAndrogen receptor / 0.947
2ama DHTAndrogen receptor / 0.914
2pix DHTAndrogen receptor / 0.903
2pio DHTAndrogen receptor / 0.896
1t65 DHTAndrogen receptor / 0.895
1t7m DHTAndrogen receptor / 0.881
2q7i TESAndrogen receptor / 0.879
1t73 DHTAndrogen receptor / 0.875
1t7f DHTAndrogen receptor / 0.859
4hlw TESAndrogen receptor / 0.854
2q7k TESAndrogen receptor / 0.850
2ylp TESAndrogen receptor / 0.842
4oed DHTAndrogen receptor / 0.841
2z4j DHTAndrogen receptor / 0.825
2pit DHTAndrogen receptor / 0.819
4oea DHTAndrogen receptor / 0.809
1t63 DHTAndrogen receptor / 0.807
1t76 DHTAndrogen receptor / 0.800
2pir DHTAndrogen receptor / 0.788
4ofr DHTAndrogen receptor / 0.786
2pnu ENMAndrogen receptor / 0.779
4ofu DHTAndrogen receptor / 0.767
4e5l DBHPolymerase acidic protein / 0.754
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2piu DHTAndrogen receptor / 0.741
2piv DHTAndrogen receptor / 0.741
1gs4 ZK5Androgen receptor / 0.717
2qpy DHTAndrogen receptor / 0.713
3up0 D7SaceDAF-12 / 0.704
1g50 ESTEstrogen receptor / 0.702
1t7t DHTAndrogen receptor / 0.692
3uzx AOM3-oxo-5-beta-steroid 4-dehydrogenase / 0.691
2q7j TESAndrogen receptor / 0.688
1qyw 5SDEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.684
2q7l TESAndrogen receptor / 0.684
1xu7 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.678
3uzz ASD3-oxo-5-beta-steroid 4-dehydrogenase / 0.677
4q0a 4OAVitamin D3 receptor A / 0.676
1lhw ESMSex hormone-binding globulin / 0.675
3uzx AOX3-oxo-5-beta-steroid 4-dehydrogenase / 0.675
1lho AOMSex hormone-binding globulin / 0.673
2j7x ESTEstrogen receptor beta / 0.673
2d09 FLVBiflaviolin synthase CYP158A2 / 0.671
2ylq TESAndrogen receptor / 0.664
3w5t LHPVitamin D3 receptor / 0.663
3w5p 4OAVitamin D3 receptor / 0.660
2ylo TESAndrogen receptor / 0.657
2am9 TESAndrogen receptor / 0.652
1xf0 ASDAldo-keto reductase family 1 member C3 / 0.650